Biotin-PEG2-aldehyde
This product is a PEG linker containing a biotin group, a PEG2 spacer, and a terminal aldehyde. It enables streptavidin binding and carbonyl conjugation, making it especially valuable in probe development, detection, and bioconjugation workflows.
Key Features and Benefits
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Biotin Group: Provides strong affinity binding to streptavidin and avidin.
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Aldehyde Group: Couples with amines or hydrazides via reductive amination or oxime ligation.
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PEG2 Spacer: Enhances solubility and minimizes steric hindrance.
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Dual Reactivity: Combines affinity capture with aldehyde-based conjugation.
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High Purity: Ensures reproducible results in sensitive labeling applications.
Applications
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Bioconjugation: Links biotin-binding systems with amine- or hydrazide-modified molecules.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Detection Assays: Provides strong affinity tagging for streptavidin-based systems.
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Drug Delivery: Serves as a PEGylated scaffold with dual reactivity.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates strong biotin–streptavidin affinity with aldehyde chemistry in a compact PEG2 scaffold, specifically providing a versatile tool for labeling and conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
