Biotin-PEG12-acid
This product is a heterobifunctional PEG12 linker with a biotin moiety and a terminal carboxylic acid. The PEG12 spacer provides excellent hydrophilicity, flexibility, and extended spacing, while the biotin ensures strong binding to avidin/streptavidin systems for targeted bioconjugation and affinity labeling.
Key Features and Benefits:
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Biotin Moiety: High-affinity binding to avidin and streptavidin proteins.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG12 Spacer: Offers long hydrophilic spacing, enhanced solubility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
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Dual Functionality: Combines biotin-based affinity labeling with versatile carboxyl reactivity.
Applications:
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Affinity Labeling: Biotinylation of proteins, peptides, and biomolecules.
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Bioconjugation: Dual-functional linker for targeted labeling and probe design.
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Drug Delivery: PEGylated linker improves solubility, stability, and targeting efficiency.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and biosensors.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain acid stability.
This product provides strong biotin binding and reactive carboxyl functionality with extended PEG spacing, making it an especially versatile tool for bioconjugation, drug delivery, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
