Biotin-PEG-Azide, MW 5K is a high-quality and versatile bioconjugation reagent widely used in pharmaceutical research and development. This tri-functional molecule features three distinct functional groups: biotin, PEG, and azide.
Biotin, a vitamin B7 derivative, exhibits strong and specific binding to streptavidin and avidin, providing excellent immobilization and detection capabilities. The polyethylene glycol (PEG) linker enhances solubility, reduces immunogenicity, and increases in vivo stability of conjugated biomolecules. The azide moiety enables bioorthogonal click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating rapid and selective conjugation to alkyne-functionalized molecules.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.