Benzyl-PEG4-acid linker contains a benzyl group and a carboxylic acid group. While the carboxylic acid group can react with primary amine groups in the presence of EDC, DCC or other coupling reagents to form a stable amide bond, the benzyl groups can be removed under mild condition to form an alcohol for further derivatization. The hydrophilic PEG linker increases the solubility of the compound in aqueous media.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.