Azido-PEG9-amine
This product is a heterobifunctional PEG9 linker with a terminal azide for click chemistry and a primary amine for amide coupling. The PEG9 spacer provides hydrophilicity, flexibility, and medium-range spacing, making it an especially versatile reagent for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Azide Group: Enables CuAAC and SPAAC click chemistry with alkynes.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and electrophiles.
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PEG9 Spacer: Provides solubility, flexibility, and steric accessibility.
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High Purity: Ensures reproducibility in bioconjugation workflows.
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Dual Reactivity: Supports orthogonal and multistep conjugation strategies.
Applications:
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Bioconjugation: Dual-functional linker for proteins, peptides, and biomolecules.
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Click Chemistry: Bioorthogonal azide–alkyne ligation for labeling and probe design.
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Drug Delivery: Improves solubility, pharmacokinetics, and stability of conjugates.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide and amine stability.
This product combines click-ready azide chemistry with an amine-reactive group in a medium-length PEG chain, making it especially ideal for dual bioconjugation and multifunctional material design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
