Azido-PEG8-Hydrazide
Azido-PEG8-Hydrazide is a high-purity heterobifunctional linker containing an azide group for copper-catalyzed or strain-promoted azide–alkyne cycloaddition (CuAAC or SPAAC) click chemistry, and a hydrazide group for conjugation with aldehydes or ketones to form hydrazone linkages. The PEG8 spacer specifically improves solubility and flexibility, reducing steric hindrance in bioconjugation workflows.
Key Features
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Azide group for CuAAC or SPAAC click chemistry
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Hydrazide for aldehyde/ketone conjugation via hydrazone bond
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PEG8 spacer for enhanced solubility and reduced steric interference
Applications
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Protein, peptide, and antibody modification
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Glycoconjugation and glycoprotein labeling
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Preparation of multifunctional biomolecule conjugates
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Warm to room temperature before use to avoid condensation
This product offers orthogonal reactivity through its azide and hydrazide groups, making it an especially versatile tool for combining click chemistry with carbonyl-based conjugation in aqueous or organic environments.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
