Azido-PEG8-CH2CO2-PFP is a PEG derivative that contains an azide group and a PFP group. The azide group readily reacts with alkyne, BCN, DBCO through Click Chemistry to yield a stable triazole linkage. The PFP ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Unlike NHS ester, the PFP ester is less susceptible toward hydrolysis.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.