Azido-PEG8-amine
This product is a heterobifunctional PEG8 linker with a terminal azide for click chemistry and a primary amine for amide coupling. The PEG8 spacer provides hydrophilicity, flexibility, and moderate spacing, making it especially suitable for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Azide Group: Enables CuAAC or SPAAC click chemistry with alkyne partners.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and electrophiles.
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PEG8 Spacer: Balances solubility, flexibility, and steric accessibility.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Supports orthogonal and stepwise conjugation strategies.
Applications:
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Bioconjugation: Enables efficient dual labeling of proteins, peptides, and biomolecules.
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Click Chemistry: Azide–alkyne ligation for bioorthogonal conjugation.
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Drug Delivery: PEGylated linker enhances solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide and amine reactivity.
This product provides dual-reactive groups with a medium-length PEG spacer, making it an especially versatile tool for orthogonal conjugation and advanced material science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
