Azido-PEG8-acid
This product is a heterobifunctional PEG8 linker with a terminal azide for click chemistry and a carboxylic acid for amide coupling. The PEG8 spacer provides hydrophilicity, flexibility, and medium-length spacing, making it especially suitable for bioconjugation, drug delivery, and surface functionalization.
Key Features and Benefits:
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Azide Group: Enables CuAAC and SPAAC click chemistry with alkynes.
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Carboxylic Acid Group: Couples efficiently with primary amines for stable amide bonds.
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PEG8 Spacer: Offers solubility, flexibility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Combines bioorthogonal click chemistry with amide bond formation.
Applications:
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Click Chemistry: Bioorthogonal azide–alkyne ligation for labeling and conjugation.
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Bioconjugation: Facilitates protein, peptide, and biomolecule modification.
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Drug Delivery: PEGylated linker enhances solubility, pharmacokinetics, and stability.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide and acid reactivity.
This product combines click-ready azide chemistry with carboxyl reactivity in a medium-length PEG chain, making it an especially versatile reagent for multifunctional conjugation and drug delivery applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
