Azido-PEG6-amine
This product is a bifunctional PEG6 linker with a terminal azide for click chemistry and a primary amine for amide coupling. The PEG6 spacer enhances solubility and flexibility, making it an especially versatile tool for orthogonal conjugation, drug delivery, and surface functionalization.
Key Features and Benefits:
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Azide Group: Supports CuAAC or SPAAC click chemistry with alkyne partners.
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Amine Group: Couples with carboxyls, NHS esters, and other electrophiles.
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PEG6 Spacer: Provides hydrophilicity, reduced steric hindrance, and flexibility.
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High Purity: Ensures reproducibility in bioconjugation workflows.
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Dual Reactivity: Allows orthogonal and stepwise synthesis strategies.
Applications:
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Bioconjugation: Dual-reactive linker for proteins, peptides, and biomolecules.
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Click Chemistry: Azide–alkyne ligation for bioorthogonal labeling.
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Drug Delivery: Enhances solubility and pharmacokinetics of conjugates.
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Surface Modification: Functionalizes nanoparticles, hydrogels, or polymers.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain reactivity.
This product combines click-ready azide functionality with a reactive amine, specifically providing a balanced PEG spacer for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
