Azido-PEG36-alcohol
This product is a heterobifunctional linker containing a terminal azide, a 36-unit PEG chain, and a terminal hydroxyl group. The azide enables copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click chemistry with alkynes or cyclooctynes, while the hydroxyl group provides a versatile handle for further derivatization. The long PEG36 spacer imparts excellent solubility, flexibility, and extended spacing, making this reagent especially useful in bioconjugation, drug delivery, and nanotechnology.
Key Features and Benefits
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Azide Group: Supports CuAAC or SPAAC click chemistry with alkynes.
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Hydroxyl Group: Serves as a functional handle for derivatization.
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PEG36 Spacer: Provides hydrophilicity, flexibility, and extended reach.
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Dual Reactivity: Combines click chemistry with hydroxyl-based modification.
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High Purity: Produced to ≥95% purity for reproducibility.
Applications
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Bioconjugation: Links alkynes or cyclooctynes to hydroxyl-modified partners.
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Drug Delivery: Acts as a long, hydrophilic linker for therapeutic conjugates.
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Probe Development: Builds multifunctional probes with extended PEG spacing.
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Nanotechnology: Functionalizes nanoparticles or surfaces with azide and hydroxyl handles.
Storage and Handling
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use freshly prepared solutions; avoid repeated freeze–thaw cycles.
This product combines long PEG spacing with azide click reactivity and hydroxyl versatility, making it an especially excellent tool for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
