Azido-PEG3-triethoxysilane
This product is a heterobifunctional linker containing a terminal azide group, a short PEG3 spacer, and a triethoxysilane moiety. The azide supports copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click chemistry with alkynes, while the triethoxysilane enables covalent attachment to glass, silica, or metal oxide surfaces. The PEG3 chain improves solubility and flexibility, reducing steric hindrance and nonspecific interactions, making this reagent especially ideal for surface functionalization and biointerface engineering.
Key Features and Benefits
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Azide Group: Enables CuAAC or SPAAC click chemistry with alkyne partners.
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Triethoxysilane Moiety: Forms stable covalent bonds with glass, silica, or oxide surfaces.
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PEG3 Spacer: Enhances solubility, flexibility, and biocompatibility.
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Dual Reactivity: Supports orthogonal surface coupling and click chemistry.
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High Purity: Produced to ≥95% purity for reproducibility.
Applications
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Surface Functionalization: Attaches bioactive molecules to glass or nanoparticle surfaces.
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Bioconjugation: Couples azide-bearing surfaces with alkyne-modified biomolecules.
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Nanotechnology: Functionalizes silica nanoparticles or oxide-coated materials.
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Diagnostics: Builds functionalized surfaces for biosensors and assays.
Storage and Handling
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Storage: Store at 2–8 °C in a sealed container, protected from moisture.
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Handling: Use under dry conditions; hydrolyzes in aqueous environments.
This product combines surface anchoring and azide click reactivity in a short PEG framework, specifically offering a versatile reagent for controlled surface modification and bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
