Azido-PEG3-SSPy is a cleavable linker for bioconjugation, combining an azide group for click chemistry with alkynes, an SSPy (pyridyl disulfide) group for thiol binding, and a PEG3 spacer that enhances solubility.
Key Features:
- Azide Group: Enables click reactions with alkyne molecules.
- SSPy Group: Binds to thiol groups, forming reversible disulfide bonds.
- PEG3 Spacer: Increases solubility and flexibility, reducing steric hindrance.
Applications:
- Antibody-Drug Conjugates (ADCs): Links drugs to antibodies for targeted therapy.
- Protein and Peptide Conjugation: Attaches proteins or peptides to molecules or surfaces.
- Surface Functionalization: Adds functional groups to surfaces for biosensors.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.