Azido-PEG3-CH2CO2H
This product is a heterobifunctional PEG linker featuring a terminal azide group for click chemistry and a carboxylic acid for amide conjugation. The PEG3 spacer improves solubility and flexibility, making it especially useful in bioconjugation, probe design, and drug delivery applications.
Key Features and Benefits:
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Azide Group: Enables CuAAC or SPAAC click chemistry with alkynes.
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Carboxylic Acid: Couples efficiently with primary amines for stable amide bonds.
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PEG3 Spacer: Enhances solubility, hydrophilicity, and steric accessibility.
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Dual Reactivity: Supports orthogonal and multifunctional conjugation.
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High Purity: Provides reliable performance in advanced workflows.
Applications:
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Bioconjugation: Links biomolecules via click and amide chemistry.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEGylated linkers for therapeutic conjugates.
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Material Science: Functionalizes polymers, nanoparticles, and advanced surfaces.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain reactivity.
This product integrates a click-ready azide with an amine-reactive carboxyl group in a PEG3 scaffold, specifically offering versatile chemistry for conjugation and advanced applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
