Azido-PEG16-Hydrazide
Azido-PEG16-Hydrazide is a high-purity heterobifunctional PEG linker with an azide group for copper-catalyzed or strain-promoted click chemistry and a hydrazide group for conjugation with aldehydes or ketones. The PEG16 spacer specifically enhances water solubility, flexibility, and reduces steric hindrance, making it suitable for a wide range of bioconjugation applications.
Key Features
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Azide group for click chemistry reactions (CuAAC or SPAAC)
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Hydrazide group for conjugation with carbonyl-containing molecules
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PEG16 spacer for high solubility and low immunogenicity
Applications
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Protein and antibody labeling
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Biomolecule immobilization on solid supports
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Drug delivery and diagnostic probe development
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Bring to room temperature before opening to minimize moisture uptake
This product provides dual functionality for orthogonal conjugation strategies, combining click chemistry with carbonyl-reactive coupling. The PEG16 chain offers enhanced solubility and reduced steric hindrance, making it especially ideal for complex bioconjugation and material science applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.