Azido-PEG15-t-butyl ester is a high-purity, bifunctional polyethylene glycol (PEG) derivative featuring an azide group and a t-butyl ester-protected carboxyl group. This molecule is widely used in bioconjugation, click chemistry, and surface modification applications. Moreover, the PEG15 spacer enhances water solubility and provides a flexible linker, making it highly valuable in drug delivery systems, polymer modification, and bioorthogonal reactions.
Key Features
- Bifunctional Reactivity – Contains both an azide group for click chemistry and a t-butyl ester-protected carboxyl for controlled deprotection, thereby offering enhanced versatility.
- Enhanced Water Solubility – The PEG15 spacer significantly improves solubility, ensuring better performance in aqueous environments.
- Versatile Linker – Provides an optimal spacer length, which is crucial for conjugation and molecular engineering applications.
- High Purity and Stability – Manufactured under stringent quality control, thus ensuring consistent and reliable results.
- Bioorthogonal Compatibility – Ideally suited for use in bioorthogonal labeling and functionalization techniques, further expanding its applications.
Applications
- Click Chemistry Reactions – Facilitates bioorthogonal conjugation in chemical and biological research, making it highly valuable for diverse studies.
- Drug Delivery Systems – Enhances drug solubility and bioavailability, thereby improving therapeutic performance.
- Polymer and Surface Modification – Functionalizes surfaces and polymers for targeted biomedical applications, which can lead to improved material properties.
- Bioconjugation and Labeling – Enables attachment of biomolecules, thus supporting advanced research and therapeutic development.
Conclusion
In summary, Azido-PEG15-t-butyl ester is a highly effective linker and reagent for bioconjugation, click chemistry, and surface modification. With its enhanced solubility, bifunctional reactivity, and stability, this PEG derivative provides a reliable solution for researchers and developers working on drug delivery, polymer engineering, and molecular labeling. Therefore, its versatility makes it an indispensable tool in pharmaceutical and biotechnology applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
