Azido-PEG11-amine
This product is a heterobifunctional PEG11 linker with a terminal azide for click chemistry and a primary amine for amide coupling. The PEG11 spacer provides hydrophilicity, flexibility, and extended spacing, making it especially versatile for bioconjugation, drug delivery, and multifunctional material science.
Key Features and Benefits:
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Azide Group: Enables CuAAC and SPAAC click chemistry with alkyne partners.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and electrophiles.
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PEG11 Spacer: Provides solubility, flexibility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Combines click-ready azide chemistry with amine reactivity for multifunctional conjugation.
Applications:
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Bioconjugation: Dual-functional linker for proteins, peptides, and biomolecules.
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Click Chemistry: Azide–alkyne ligation for selective and bioorthogonal labeling.
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Drug Delivery: PEGylated linker improves solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide and amine stability.
This product offers dual-reactivity in a medium-to-long PEG chain, making it an especially powerful tool for click chemistry, drug delivery, and biomaterial engineering.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.