Azido-PEG11-acid
This product is a bifunctional PEG11 linker with a terminal azide for click chemistry and a carboxylic acid for amide coupling. This dual reactivity makes it especially ideal for orthogonal bioconjugation, drug delivery, and surface modification applications.
Key Features and Benefits:
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Azide Group: Enables CuAAC or SPAAC click chemistry with alkynes.
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Carboxylic Acid Group: Couples efficiently with primary amines.
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PEG11 Spacer: Improves solubility, flexibility, and reduces steric hindrance.
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High Purity: Ensures reproducibility in research and therapeutic development.
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Dual Reactivity: Supports stepwise and orthogonal conjugation strategies.
Applications:
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Click Chemistry: Bioorthogonal labeling with alkyne-containing molecules.
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Bioconjugation: Dual-functional linker for protein, peptide, or polymer conjugates.
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Drug Delivery: Spacer-linker for improved pharmacokinetics and payload attachment.
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Surface Modification: Functionalizes nanoparticles, hydrogels, and biomaterials.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain reactivity.
This product provides a hydrophilic PEG spacer with azide and acid handles, making it an especially versatile linker for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
