Azido-PEG10-acid
This product is a heterobifunctional PEG10 linker with a terminal azide for click chemistry and a carboxylic acid for amide coupling. The PEG10 spacer provides hydrophilicity, flexibility, and medium-to-long spacing, making it especially useful for bioconjugation, drug delivery, and advanced material applications.
Key Features and Benefits:
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Azide Group: Enables CuAAC and SPAAC click chemistry with alkyne partners.
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Carboxylic Acid Group: Couples efficiently with primary amines to form stable amide bonds.
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PEG10 Spacer: Provides balanced solubility, spacing, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Reactivity: Combines bioorthogonal click chemistry with amide coupling functionality.
Applications:
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Click Chemistry: Bioorthogonal azide–alkyne ligation for labeling and probe design.
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Bioconjugation: Facilitates dual-functional attachment of proteins, peptides, and biomolecules.
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Drug Delivery: PEGylated linker enhances solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain azide and acid integrity.
This product provides a versatile medium-length PEG spacer with click-ready and amide-reactive groups, making it an especially excellent choice for multifunctional bioconjugation and drug delivery workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
