Azido-PEG1-methylamine is a PEG derivative containing an azide group and methylamine group. The hydrophilic PEG spacer can increase solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The methylamine group readily reacts with carboxylic acids, activated NHS esters under amide coupling conidtion and carbonyls (ketone and aldehyde) to form imidine or amine after reducttion.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.