Azido-PEG1-amine
This product is a compact heterobifunctional PEG linker with a terminal azide and a primary amine, separated by a single ethylene glycol unit. The azide enables copper-catalyzed or copper-free click chemistry with alkynes, while the amine allows conjugation through amide bond formation. Its short PEG1 spacer provides minimal flexibility and spacing, making it especially ideal for compact labeling and controlled modifications.
Key Features and Benefits
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Azide Group: Reacts with alkynes via CuAAC or SPAAC for efficient click chemistry.
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Primary Amine: Couples readily with carboxyl or NHS ester groups.
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PEG1 Spacer: Compact design reduces linker length while maintaining solubility.
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Dual Reactivity: Offers orthogonal handles for sequential or multifunctional conjugations.
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High Purity: Manufactured to ≥95% purity for reliable and reproducible results.
Applications
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Bioconjugation: Couples azide- and amine-reactive partners in a single linker system.
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Probe Development: Builds compact dual-functional probes for imaging and diagnostics.
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Drug Delivery: Serves as a linker for PEGylated therapeutics with orthogonal reactivity.
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Surface Modification: Introduces azide and amine groups to polymers and nanomaterials.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Use freshly prepared solutions; avoid repeated freeze–thaw cycles.
This product combines azide click functionality with amine reactivity in a compact PEG1 spacer, specifically providing a versatile linker for multifunctional bioconjugation and synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
