Azide-PEG3-Sulfone-PEG3-azide
This product is a symmetric PEG linker featuring dual terminal azides for click chemistry, connected by a sulfone bridge and PEG3 spacers. This design combines bioorthogonal reactivity with a stable, polar sulfone core, making it especially valuable for bioconjugation, drug delivery, and multifunctional probe development.
Key Features and Benefits:
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Dual Azides: Enable CuAAC or SPAAC click chemistry with alkynes.
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Sulfone Bridge: Provides chemical stability and hydrophilic polarity.
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PEG3 Spacers: Enhance solubility, flexibility, and steric accessibility.
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Symmetric Design: Supports dual modification or crosslinking.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
Applications:
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Bioconjugation: Couples biomolecules through dual click-ready handles.
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Drug Delivery: Enables multifunctional payload assembly with PEG solubility.
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Probe Development: Builds stable, symmetric probes for imaging and diagnostics.
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Synthetic Chemistry: Serves as a versatile crosslinker or intermediate.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide reactivity.
This product integrates dual azides with a sulfone bridge specifically for versatile click chemistry applications, providing solubility, stability, and multifunctional crosslinking potential.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
