Azide-PEG-amine, MW 10K is a heterobifunctional azide PEG amine product used in click chemistry, often used as a crosslinker or as a spacer between two different chemical entities. Azides can be reacted with terminal alkynes for copper-catalyzed click chemistry or with DBCO/BCN for copper-free click chemistry. The amine group reacts with the activated NHS ester to form a stable amide bond. The PEG moiety in the heterofunctional PEG derivatives provides water solubility, biocompatibility and flexibility. Applications are particularly suitable for the development of antibody drug conjugates (ADCs).
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
