APN-C3-Biotin (CAS: 2170240-97-6) is a heterobifunctional linker that combines an APN (4-azidophenyl) moiety with biotin for APN-cysteine conjugates.
Key Features:
- Selective Reactivity: The APN group exhibits high chemoselectivity toward cysteine residues, facilitating targeted conjugation.
- Biotin Tagging: The biotin component allows for easy detection and purification using streptavidin-based methods.
- Stability: APN-cysteine conjugates demonstrate superior stability in aqueous media, human plasma, and living cells, enhancing their utility in various biological contexts.
Applications:
- Protein Labeling: Used for tagging proteins at specific cysteine residues.
- Bioconjugation Studies: In research involving protein-protein interactions and cellular processes.
- Diagnostic Assays: Utilized in assays requiring biotin-streptavidin interactions.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.