Aminooxy-PEG1-propargyl HCl salt contains a propargyl group and an aminooxy group. While the aminooxy group reacts with an aldehyde or ketone group to form a reversible oxime linkage, the propargyl group readily reacts with azide-derivatized biomolecules via copper catalyzed Click Chemistry. The increasing aqueous solubility derived from the PEG spacer further expand its application in bioconjugations.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.