Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane
This product is a high-purity trifunctional linker with a primary amine and three tert-butoxycarbonyl (t-Boc) protected hydroxyl groups. The t-Boc groups specifically provide controlled deprotection under mild acidic conditions to reveal reactive hydroxyl functionalities for further derivatization. This architecture enables multi-point attachment or branching, making it especially ideal for dendrimer synthesis, multi-valent bioconjugation, and advanced material design.
Key Features and Benefits
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Primary Amine: Reacts efficiently with carboxylic acids, NHS esters, or other electrophiles.
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t-Boc Protected Hydroxyls: Allow controlled deprotection to yield free hydroxyl groups for subsequent modification.
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Trifunctional Core: Enables multi-valent or branched conjugation strategies.
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High Purity: Supplied at >95% purity for consistent performance.
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Versatile Reactivity: Suitable for both aqueous and organic synthesis workflows.
Applications
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Dendrimer and branched polymer synthesis.
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Multi-valent ligand or drug conjugation.
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Biomaterial and hydrogel functionalization.
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Crosslinker design for polymer networks.
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Multi-site labeling in biochemical research.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid moisture to maintain reactivity and Boc protection.
Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane combines a primary amine with three protected hydroxyls specifically for controlled, multi-site functionalization in dendrimer synthesis, bioconjugation, and materials engineering.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
