Amino-PEG8-Amine (NH2-PEG8-NH2), CAS number 82209-36-7, is a bifunctional PEG linker with amine groups on both ends of an 8-unit PEG chain.
Key Features:
- Structure: The PEG chain has eight ethylene glycol units, each ending with a primary amine group. This design allows for easy and efficient conjugation.
- Reactivity: The amine groups react quickly with carboxyl groups, NHS esters, and aldehydes, forming strong amide bonds. This makes it perfect for various bioconjugation and crosslinking needs.
- Applications:
- Bioconjugation: It easily links to proteins, peptides, and biomolecules through its reactive amine groups.
- Crosslinking: Ideal for crosslinking in biomaterials, creating functional bonds between molecules.
- Drug Delivery: It enhances solubility and extends circulation time, acting as a flexible spacer in drug delivery systems.
- Surface Modification: It modifies surfaces to improve biocompatibility in medical devices and biosensors.
- Solubility: The PEG8 chain offers excellent water solubility and flexibility, reducing non-specific interactions and boosting compatibility with biological systems.
Summary:
Amino-PEG8-Amine (NH2-PEG8-NH2) is a highly versatile PEG linker. It supports bioconjugation, crosslinking, and drug delivery applications, thanks to its solubility, flexibility, and biocompatibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
