Amino-PEG8-Alcohol (NH2-PEG8-OH) (CAS: 352439-37-3): Overview and Applications
Amino-PEG8-Alcohol (NH2-PEG8-OH) (CAS: 352439-37-3) is a polyethylene glycol (PEG) derivative featuring an amino group and a terminal alcohol. This compound enhances solubility and biocompatibility, making it valuable for various applications in chemical biology and drug development.
Key Features:
- Amino Group: Provides a reactive site for coupling with other biomolecules, facilitating bioconjugation.
- PEG Spacer: The eight-unit PEG chain enhances solubility in aqueous environments and reduces immunogenicity.
- Hydroxyl Termination: Offers further modification options and enhances solubility.
Applications:
- Bioconjugation: Used to link proteins, peptides, and nucleic acids for targeted delivery.
- Drug Development: Improves the stability and solubility of therapeutics.
- Surface Modification: Modifies surfaces in biosensors and other biomaterials.
- Chemical Biology: Useful for studying protein interactions and cellular processes.
Amino-PEG8-Alcohol is essential for developing advanced drug delivery systems and bioconjugation strategies in research and biotechnology.
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