Amino-PEG4-CH2COOH
This product is a high-purity heterobifunctional PEG linker with a terminal amine and a carboxylic acid specifically separated by a PEG4 spacer for solubility and flexibility.
Key Features and Benefits
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Terminal Amine – Reactive site for NHS ester or isocyanate coupling.
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Carboxylic Acid Group – Suitable for EDC/NHS-mediated conjugation with primary amines.
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PEG4 Spacer – Enhances solubility, reduces steric hindrance, and improves linker flexibility.
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High Purity – Suitable for bioconjugation, material modification, and drug delivery applications.
Applications
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Crosslinking proteins, peptides, or antibodies
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Surface modification and biomaterial functionalization
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Drug delivery and nanoparticle conjugation
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Dual functional handle for orthogonal conjugation strategies
Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents such as DMSO or DMF. Avoid repeated freeze–thaw cycles.
This product provides both an amine and carboxyl group on a PEG4 spacer, specifically enabling versatile conjugation strategies with enhanced solubility and flexibility.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.