Amino-PEG4-alcohol
This product is a bifunctional PEG4 linker with a primary amine and a terminal hydroxyl group. The PEG4 spacer enhances solubility and flexibility, making it an especially versatile reagent for bioconjugation, drug delivery, and material modification.
Key Features and Benefits:
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Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
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Hydroxyl Group: Serves as a handle for further functionalization or activation.
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PEG4 Spacer: Improves hydrophilicity, flexibility, and reduces steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Dual Reactivity: Supports orthogonal and stepwise synthesis strategies.
Applications:
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Bioconjugation: Attach biomolecules with controlled PEG spacing.
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Drug Delivery: PEGylated linker enhances solubility and pharmacokinetics.
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Surface Modification: Functionalize nanoparticles, hydrogels, or polymers.
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Synthetic Chemistry: Intermediate for PEG-based scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C, protected from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF) to maintain amine and hydroxyl stability.
This product combines a reactive amine with a hydroxyl handle in a short PEG spacer, specifically providing a compact, versatile linker for bioconjugation and advanced synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.