Amino-PEG36-acid
This product is a long-chain bifunctional PEG36 linker with a terminal amine and a carboxylic acid. The extended PEG36 spacer provides excellent hydrophilicity, flexibility, and long-range spacing, making it especially useful for bioconjugation, drug delivery, and surface functionalization.
Key Features and Benefits:
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Amine Group: Couples with carboxyls, NHS esters, and other electrophiles.
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Carboxylic Acid Group: Forms stable amide bonds with primary amines.
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PEG36 Spacer: Provides maximum hydrophilicity, flexibility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Reactivity: Supports orthogonal and stepwise conjugation strategies.
Applications:
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Bioconjugation: Attach proteins, peptides, or biomolecules with long-chain spacing.
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Drug Delivery: Improves solubility and pharmacokinetic properties of therapeutic payloads.
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Surface Modification: Functionalize nanoparticles, hydrogels, or biomaterials.
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Material Science: Incorporate into PEGylated polymers and scaffolds for advanced materials.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain amine and acid reactivity.
This product provides long-chain PEG spacing with dual-reactive handles, making it an especially versatile reagent for advanced conjugation and material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.