Amino-PEG28-acid
This product is a long-chain bifunctional PEG linker with a reactive terminal amine and a carboxylic acid. The extended PEG28 spacer provides excellent hydrophilicity, flexibility, and long-chain spacing, making it especially useful for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
-
Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
-
Carboxylic Acid Group: Forms stable amide bonds with primary amines.
-
PEG28 Spacer: Provides extended hydrophilicity, reduced steric hindrance, and long-chain flexibility.
-
High Purity: Suitable for sensitive and reproducible workflows.
-
Dual Reactivity: Enables stepwise and orthogonal conjugation strategies.
Applications:
-
Bioconjugation: Link proteins, peptides, or small molecules with controlled spacing.
-
Drug Delivery: Long PEG spacer enhances solubility and pharmacokinetic profiles.
-
Surface Functionalization: Modify nanoparticles, hydrogels, or polymers.
-
Material Science: Integrate into PEGylated polymers and biomaterials.
Storage and Handling:
-
Storage: Store at –20 °C in a dry, light-protected container.
-
Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain reactivity.
This product combines dual-reactive groups with a long PEG chain, offering excellent solubility and spacing specifically for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
