Amino-PEG2-CH2COOH
Amino-PEG2-CH2COOH is a high-purity heterobifunctional PEG linker with a terminal primary amine on one end and a carboxylic acid group on the other. The PEG2 spacer increases water solubility, enhances molecular flexibility, and reduces steric hindrance, making it especially suitable for diverse bioconjugation strategies in both aqueous and organic environments.
Key Features
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Primary amine and carboxylic acid for orthogonal conjugation
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PEG2 spacer improves hydrophilicity and flexibility
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High chemical stability and purity
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Compatible with aqueous and organic systems
Applications
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Protein and peptide crosslinking
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Antibody–drug conjugate (ADC) synthesis
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Nanoparticle and surface modification
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Biomaterial functionalization
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Bring to room temperature before use
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Avoid repeated freeze–thaw cycles
This product has a primary amine and a carboxylic acid for orthogonal coupling, with a PEG2 spacer specifically for better solubility and reduced steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
