Amino-PEG1-amine
This product is a homobifunctional PEG linker containing two terminal primary amines connected by a PEG1 spacer. It specifically enables amide coupling, crosslinking, and surface modification, offering compact length, solubility, and strong reactivity.
Key Features and Benefits
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Dual Primary Amines: Couple efficiently with carboxyls, NHS esters, or activated linkers.
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PEG1 Spacer: Provides compact spacing with minimal steric hindrance.
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Homobifunctional Design: Enables symmetric crosslinking of biomolecules or polymers.
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High Reactivity: Facilitates rapid conjugation under mild conditions.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
Applications
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Bioconjugation: Links biomolecules through amide coupling with carboxyl partners.
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Crosslinking: Bridges proteins, peptides, or polymers via dual amine groups.
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Probe Development: Builds symmetric PEGylated probes for diagnostics and imaging.
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Material Science: Functionalizes surfaces, nanoparticles, and hydrogels with amine handles.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates dual primary amines in a compact PEG1 scaffold, offering solubility and high reactivity specifically for efficient conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.