Amino-11-CTP
This product is a high-purity cytidine triphosphate derivative modified with an aminohexyl linker at the C5 position, extended by an 11-atom spacer for especially versatile conjugation. It retains the triphosphate group for enzymatic incorporation into RNA.
Key Features and Benefits
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Cytidine Triphosphate Core – Functions as a natural substrate for RNA polymerases.
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Aminohexyl Spacer (11 atoms) – Provides a reactive primary amine for coupling with NHS esters, carboxyls, and activated carbonates.
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Extended Linker – Enhances accessibility of the amino group for downstream labeling.
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High Purity – Suitable for enzymatic reactions, labeling, and assay development.
Applications
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Incorporation into RNA by in vitro transcription.
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Site-specific labeling of RNA with fluorescent dyes or affinity tags.
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Probe development for RNA structure and function studies.
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Bioconjugation for diagnostics and therapeutics.
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in nuclease-free water or buffer. Avoid repeated freeze–thaw cycles.
This product is a cytidine nucleotide analog bearing an extended amino linker, enabling efficient enzymatic incorporation and versatile conjugation specifically for RNA labeling and functionalization.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
