Ald-Ph-PEG5-t-butyl ester CAS:1433996-83-8 is a bifunctional PEG linker, featuring an aromatic aldehyde (Ald-Ph) and a t-butyl ester group. The aldehyde functionality enables selective conjugation to amine-containing molecules, while the t-butyl ester group facilitates hydrolysis under mild acidic conditions. This versatile linker finds utility in drug delivery and bioconjugation applications.
In pharmaceutical research and development, Ald-Ph-PEG5-t-butyl ester serves as a powerful tool for constructing prodrugs and targeted therapeutics. Its unique bifunctionality facilitates the coupling of active pharmaceutical ingredients to targeting ligands, enhancing drug efficacy and minimizing off-target effects. The t-butyl ester group provides a cleavable linkage, ensuring controlled release of the parent drug under physiological conditions, thus optimizing therapeutic outcomes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
