Ald-Ph-PEG3-azide
This product is a heterobifunctional linker featuring an aromatic aldehyde (Ald-Ph) group for Schiff base formation and a terminal azide for click chemistry. The PEG3 spacer provides solubility and flexibility, making it especially useful for bioconjugation, probe development, and multifunctional synthetic strategies.
Key Features and Benefits:
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Aromatic Aldehyde Group: Enables reversible Schiff base formation with amines.
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Azide Group: Supports CuAAC or SPAAC click chemistry with alkynes.
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PEG3 Spacer: Enhances solubility and steric accessibility.
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Dual Reactivity: Combines aldehyde-based and click-based chemistries.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Links biomolecules via aldehyde and azide reactivity.
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Probe Development: Creates multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEGylated scaffolds with dual functional handles.
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Synthetic Chemistry: Useful in modular and orthogonal linker design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); protect from premature aldehyde oxidation.
This product integrates aldehyde-based reactivity with azide click functionality in a PEG3 scaffold, specifically offering versatility for advanced conjugation and probe design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
