Ald-PEG23-SPDP is a bifunctional reagent featuring an aldehyde group for oxime or hydrazone ligation and an SPDP group for thiol-reactive cross-linking. The PEG23 spacer provides exceptional solubility, flexibility, and reduced steric hindrance, enabling efficient bioconjugation and cross-linking in complex biological and chemical systems.
Features
- Aldehyde Group: Enables oxime or hydrazone ligation with amines or hydrazides.
- SPDP Group: Reacts with thiols for stable disulfide linkages.
- PEG23 Spacer: Enhances solubility and minimizes steric hindrance.
- High Purity: ≥95% for reliable and reproducible results.
- Biocompatibility: Suitable for sensitive biological environments.
Applications
- Bioconjugation: Dual modification of biomolecules with aldehyde and thiol chemistries.
- Cross-Linking: Thiol-specific linkages for protein and peptide conjugation.
- Drug Delivery: Synthesis of cleavable drug conjugates.
- Diagnostics: Functionalization for biosensors and assays.
- Material Science: Design of functionalized polymers and hydrogels.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
