Ald-benzoylamide-PEG4-CH2 acid
This product is a heterobifunctional PEG4 linker featuring an aldehyde-functionalized benzoylamide group and a terminal carboxylic acid. The PEG4 spacer specifically provides hydrophilicity, flexibility, and short-to-medium chain spacing, making it highly suitable for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Aldehyde Group: Reacts selectively with amines and hydrazides to form stable conjugates.
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Carboxylic Acid Group: Couples efficiently with primary amines for amide bond formation.
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PEG4 Spacer: Provides solubility and reduced steric hindrance for effective conjugation.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
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Dual Reactivity: Supports orthogonal conjugation with aldehyde and carboxyl functionalities.
Applications:
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Bioconjugation: Facilitates dual-functional biomolecule attachment.
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Drug Delivery: PEGylated linker enhances solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
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Synthetic Chemistry: Useful for stepwise conjugation strategies in multifunctional scaffolds.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain aldehyde and acid stability.
This product provides aldehyde and carboxyl groups in a compact PEG4 framework, making it an especially versatile tool for dual bioconjugation and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
