Ald-benzoylamide-PEG2-CH2 acid
This product is a high-purity heterobifunctional PEG linker featuring a terminal aldehyde and a terminal carboxylic acid, connected by a PEG2 spacer that specifically improves solubility and flexibility for bioconjugation workflows.
Key Features and Benefits
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Aldehyde Group – Enables chemoselective oxime or hydrazone ligation with aminooxy or hydrazide compounds.
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Carboxylic Acid Group – Provides a reactive site for amide bond formation with amines.
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PEG2 Spacer – Enhances aqueous solubility, reduces steric hindrance, and improves accessibility in conjugates.
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High Purity – Ensures reproducible performance in protein modification, probe design, and therapeutic development.
Applications
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Oxime or hydrazone ligation with hydrazide- or aminooxy-functionalized biomolecules
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Amide coupling for peptide, protein, or nanoparticle conjugation
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Development of multifunctional linkers in drug delivery systems
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Surface modification and probe synthesis for diagnostics
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product provides both aldehyde and carboxyl functionalities on a PEG2 spacer, making it an especially versatile, soluble, and flexible linker for oxime/hydrazone ligation, amide coupling, and advanced bioconjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
