Acid-PEG3-SS-PEG3-acid
This product is a symmetric PEG linker featuring dual terminal carboxylic acid groups connected by a central disulfide (–SS–) bond and PEG3 spacers. This design provides hydrophilicity, redox-cleavable functionality, and versatile conjugation potential, making it especially useful for bioconjugation, drug delivery, and materials science.
Key Features and Benefits:
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Dual Carboxyl Groups: Enable amide coupling with amines for stable linkages.
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Disulfide Bridge: Offers redox-cleavable, reversible conjugation.
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PEG3 Spacers: Enhance solubility, flexibility, and steric accessibility.
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Symmetric Design: Balances stability and controlled cleavage.
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High Purity: Ensures reproducibility in sensitive applications.
Applications:
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Bioconjugation: Couples biomolecules with redox-sensitive control.
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Drug Delivery: Provides cleavable PEG scaffolds for targeted release.
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Probe Development: Builds responsive probes for imaging and diagnostics.
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Material Science: Functionalizes polymers and nanoparticles with cleavable handles.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid reducing agents prior to use.
This product integrates dual acid functionality with a cleavable disulfide core, specifically offering solubility and controlled release for advanced bioconjugation and delivery systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
