8-ArmPEG-Mal, MW 10K is a highly versatile and functional molecule used in pharmaceutical research and development. This compound is composed of an eight-arm polyethylene glycol (PEG) core with a maleimide functional group at the end of each arm. The maleimide group is an important reactive moiety commonly used in bioconjugation chemistry due to its ability to selectively react with thiol groups, such as those found in cysteine residues of proteins or peptides. This unique combination of eight-arm PEG and maleimide functional groups makes 8-ArmPEG-Mal, MW 10K a highly effective tool for developing bioconjugates with proteins, peptides, and other biomolecules.
In the pharmaceutical industry, 8-ArmPEG-Mal, MW 10K is commonly used to improve the pharmacokinetic properties of therapeutic proteins and peptides, such as enhancing their stability, solubility, and half-life in the bloodstream. By conjugating these biomolecules to it, drug developers can increase their effectiveness and reduce their immunogenicity. Additionally, It can be used to develop targeted drug delivery systems by conjugating it to targeting moieties such as antibodies or peptides.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.