8-Arm PLGA-COOH, MW 10K is a biodegradable multi-arm PLGA polymer with eight terminal carboxyl groups and an approximate molecular weight of 10 kDa. Its branched structure specifically supports multivalent conjugation, drug delivery, crosslinking, and biomaterial development.
Key Features and Benefits
- 8-Arm Architecture: Creates a branched polymer structure with multiple functional arms.
- Carboxyl Functionalization: Provides terminal carboxylic acid groups for conjugation and further derivatization.
- MW 10K: Offers efficient polymer processing and flexible formulation development.
- Biodegradable: PLGA hydrolyzes into lactic acid and glycolic acid under physiological conditions.
- Multivalent Reactivity: Multiple carboxyl groups support efficient conjugation, crosslinking, and multifunctional modification.
Applications
- Bioconjugation: Activated carboxyl groups couple with amine-containing proteins, peptides, ligands, and other molecules.
- Drug Delivery: Supports biodegradable controlled-release carrier systems.
- Crosslinking: Forms functional polymer networks through carboxyl-mediated coupling reactions.\
- Nanoparticles: Supports preparation and surface functionalization of biodegradable polymeric nanoparticles.
- Biomaterials: Enables development of scaffolds, coatings, hydrogels, and other biodegradable materials.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
8-Arm PLGA-COOH, MW 10K combines biodegradable PLGA with multivalent carboxyl functionality to specifically support bioconjugation, drug delivery, crosslinking, nanoparticle functionalization, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.