8-Arm PLGA-Biotin, MW 10K is a biodegradable multi-arm PLGA polymer with terminal biotin groups and an approximate molecular weight of 10 kDa where its branched architecture specifically supports avidin-based binding, targeted delivery, surface modification, and biomaterial development.
Key Features and Benefits
- 8-Arm Architecture: Creates a branched polymer structure with multiple functional arms.
- Biotin Functionalization: Provides biotin groups for high-affinity interactions specifically with avidin and streptavidin.
- MW 10K: Offers efficient polymer processing and flexible formulation development.
- Biodegradable: PLGA hydrolyzes into lactic acid and glycolic acid under physiological conditions.
- Multivalent Binding: Multiple biotin groups support avidin-mediated assembly, immobilization, and functionalization.
Applications
- Bioconjugation: Supports avidin- or streptavidin-mediated attachment of biomolecules and functional ligands.
- Drug Delivery: Enables development of biodegradable functionalized drug delivery systems.
- Nanoparticles: Supports preparation of biotin-functionalized polymeric nanoparticles and drug carriers.
- Surface Modification: Introduces biotin functionality into PLGA-based materials for affinity binding and immobilization.
- Biomaterials: Enables development of functional scaffolds, coatings, matrices, and other biodegradable materials.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
8-Arm PLGA-Biotin, MW 10K combines biodegradable PLGA with multivalent biotin functionality to specifically support affinity-based bioconjugation, targeted delivery, nanoparticle functionalization, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.