2′-Deoxy-5′-O-DMT-5-fluorouridine 3′-CE phosphoramidite (CAS: 142246-63-7)
5′-DMT-5-F-2′-dU Phosphoramidite is a key reagent for efficient oligonucleotide synthesis. It includes a 2′-deoxy modification for stable DNA synthesis and a 5′-O-DMT group for protection during coupling. The 3′-CE phosphoramidite enables precise, high-fidelity synthesis, making it perfect for creating modified oligonucleotides.
Key Features:
- 2′-Deoxy Modification: Adds stability for better DNA synthesis.
- 5′-O-DMT Group: Protects during synthesis and ensures selective deprotection.
- 3′-CE Phosphoramidite: Ensures high-efficiency and controlled oligonucleotide assembly.
Applications:
- Oligonucleotide Synthesis: Perfect for creating DNA strands with 5-fluorouridine modifications.
- Nucleic Acid Research: Ideal for studying modified oligonucleotides.
- Therapeutic Development: Useful in synthesizing oligonucleotides for drug discovery.
Advantages:
- Efficient Coupling: The DMT group offers precise control during synthesis.
- Enhanced Stability: The 2′-deoxy modification boosts the stability of oligonucleotides.
- Versatile Use: Suitable for both research and therapeutic applications.
5′-DMT-5-F-2′-dU Phosphoramidite is ideal for researchers needing fast, reliable oligonucleotide synthesis for nucleic acid research or drug discovery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
