4arm-PEG-azide, MW 5K
4arm-PEG-azide, MW 5K is a high-purity, multi-arm PEG polymer with four terminal azide groups specifically for efficient copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click chemistry. The PEG core has an average molecular weight of 5,000 Da, providing excellent aqueous solubility, low toxicity, and flexible linker arms for high-density functionalization. This reagent is especially ideal for hydrogel crosslinking, nanoparticle modification, and multi-valent bioconjugation in both aqueous and organic systems.
Key Features and Benefits
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Four Azide Termini: Enable multi-site click conjugation with alkynes.
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PEG Core (5K MW): Provides water solubility, biocompatibility, and reduced immunogenicity.
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Multi-Arm Architecture: Supports high-density functionalization and crosslinking.
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High Purity: Supplied at >95% purity for reproducibility.
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Versatile Reactivity: Works with both CuAAC and SPAAC chemistry.
Applications
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Hydrogel and polymer network crosslinking.
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Multi-valent bioconjugation of biomolecules or ligands.
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Nanoparticle and surface functionalization.
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Drug delivery system modification.
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Scaffold construction for tissue engineering.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use clean, dry tools; avoid prolonged exposure to moisture.
This product offers four azide groups for high-density click chemistry functionalization, with a biocompatible PEG core for solubility, flexibility, and stability specifically in advanced material and bioconjugation applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
