4-Azidobenzaldehyde
4-Azidobenzaldehyde is an aromatic aldehyde with a para-position azido group. It supports both aldehyde condensation and azide click chemistry. Its compact structure and dual functionality make it ideal for probe synthesis, material modification, and advanced organic transformations.
Key Features and Benefits
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Azido Group: Enables CuAAC or SPAAC click reactions with alkynes for rapid, selective ligation.
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Aldehyde Functionality: Forms imines or hydrazones with amines/hydrazides for bioconjugation and surface chemistry.
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Bifunctional Reactivity: Combines click chemistry with aldehyde condensation for multifunctional synthesis pathways.
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Compact Aromatic Scaffold: Provides rigidity and stability for molecular design.
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High Purity: Manufactured to ≥98% purity for consistent and reproducible results.
Applications
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Bioconjugation: Couples biomolecules through aldehyde–amine linkages or azide–alkyne cycloaddition.
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Probe Development: Builds dual-reactive probes for imaging and diagnostics.
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Material Science: Introduces azido-aromatic functionality into polymers and crosslinked networks.
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Organic Synthesis: Serves as a versatile intermediate for multifunctional building blocks.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use under inert conditions when possible; avoid prolonged exposure to heat or light.
This product integrates aldehyde condensation chemistry with azide-based click reactivity in a compact aromatic framework, providing an especially powerful building block for advanced synthesis, materials, and bioconjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
