4-Arm PLGA-NH2, MW 20K is a biodegradable branched PLGA polymer with four terminal amine groups and an approximate molecular weight of 20 kDa. Its multivalent architecture specifically supports efficient conjugation, crosslinking, drug delivery, and biomaterial development.
Key Features and Benefits
- 4-Arm Architecture: Creates a branched structure with four functional PLGA arms.
- Amine Functionalization: Provides terminal primary amines for conjugation and further derivatization.\
- MW 20K: Balances polymer processability with versatile formulation and material properties.
- Versatile Reactivity: Amine groups react with NHS esters, activated carboxyl groups, and other amine-reactive compounds.
- Multivalent Platform: Four amine groups support efficient conjugation, crosslinking, and multifunctional polymer modification.
Applications
- Bioconjugation: Couples with activated proteins, peptides, ligands, dyes, and other functional molecules.
- Drug Delivery: Supports biodegradable controlled and sustained-release carrier systems.
- Crosslinking: Reacts with multifunctional electrophiles to create polymer networks and conjugates.
- Hydrogels: Forms biodegradable crosslinked networks with suitable amine-reactive components.
- Biomaterials: Supports functional nanoparticles, scaffolds, coatings, matrices, and other biodegradable materials.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to limit premature hydrolysis and polymer degradation.
4-Arm PLGA-NH2, MW 20K combines biodegradable PLGA with four reactive amine groups to specifically support efficient bioconjugation, crosslinking, drug delivery, hydrogel formation, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.