4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide
4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide is a bifunctional linker specifically with a cyanoethynyl group and a butanamide bearing a primary amine. Its multifunctional design supports click chemistry, coupling, and derivatization, making it especially valuable for probes, medicinal chemistry, and materials research.
Key Features and Benefits
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Cyanoethynyl Group: Provides a reactive alkyne–nitrile motif for conjugation and extended π-systems.
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Aromatic Core: Offers rigidity and electronic stability for probe or material design.
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Butanamide with Primary Amine: Enables amide bond formation with carboxyl or activated ester groups.
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Multifunctional Reactivity: Supports orthogonal chemistries for advanced conjugation workflows.
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High Purity: Manufactured to ≥95% purity for reliable and reproducible results.
Applications
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Bioconjugation: Couples to biomolecules or polymers through amine–amide linkages or alkyne chemistry.
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Probe Development: Serves as a building block for fluorescent or bioactive probes.
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Medicinal Chemistry: Useful intermediate for heterocyclic or small-molecule drug design.
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Materials Science: Integrates into conjugated polymers and functional materials.
Storage and Handling
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Storage: Store at –20 °C in a sealed container, away from light and moisture.
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Handling: Use freshly prepared solutions; handle under inert conditions for maximum stability.
This product combines cyanoethynyl reactivity with amine–amide functionality, specifically providing a versatile intermediate for synthesis, conjugation, and advanced research applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
