(2-methylcycloprop-2-en-1-yl)methanol
This product is a cyclopropene-based alcohol containing a strained olefin ring and a terminal hydroxymethyl group. Its strained structure provides unique reactivity in click and bioorthogonal chemistry, while the hydroxyl group offers a handle for further derivatization.
Key Features and Benefits:
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Cyclopropene Group: Strained olefin suitable for bioorthogonal click reactions with tetrazines.
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Hydroxyl Group: Versatile functional handle for esterification, etherification, or activation.
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Compact Scaffold: Small, strained carbocycle enhances reactivity.
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High Purity: Ensures reproducibility in synthetic and biochemical workflows.
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Dual Reactivity: Combines hydroxyl derivatization with cyclopropene click chemistry.
Applications:
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Bioorthogonal Chemistry: Used in tetrazine ligation for rapid labeling.
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Bioconjugation: Enables dual-reactive strategies in protein and peptide modification.
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Drug Discovery: Scaffold for designing reactive intermediates and probes.
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Synthetic Chemistry: Intermediate for cyclopropene-based functional materials.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Work under inert atmosphere to avoid unwanted side reactions.
This product provides a strained cyclopropene with a hydroxyl group, making it an especially versatile building block for bioorthogonal labeling, drug discovery, and advanced synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
